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The clinical features of KD reflect widespread inflammation of primarily medium-sized muscular arteries. Diagnosis is based upon evidence of systemic inflammation (eg, fever) in association with signs of mucocutaneous inflammation. The characteristic bilateral nonexudative conjunctivitis, erythema of the lips and oral mucosa, …Other manifestations include lower abdominal pain and cramping, low-grade fever, nausea, and anorexia [ 2,5 ]. Diarrhea may be associated with mucus or occult blood, but melena or hematochezia are rare. Fever is associated with CDI in about 15 percent of cases; temperature >38.5°C may occur in the setting of nonsevere or severe CDI.UpToDate, electronic clinical resource tool for physicians and patients that provides information on Adult Primary Care and Internal Medicine, Allergy and Immunology, Cardiovascular Medicine, Emergency Medicine, Endocrinology and Diabetes, Family Medicine, Gastroenterology and Hepatology, Hematology, Infectious Diseases, …

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UpToDate is an online resource that helps you make informed decisions about medical care. Access the latest evidence, expert opinions, and patient education with your subscription.For individuals with skin abscess, we suggest initial treatment with parenteral antibiotics in the following circumstances: Systemic signs of toxicity (eg, fever >100.5°F/38°C, hypotension, sustained tachycardia) Rapid progression of erythema or abscess. Extensive abscess or surrounding erythema.Evidence-based medicine (EBM) is the care of patients using the best available research evidence to guide clinical decision-making ( figure 1) [ 1,2 ]. The value of EBM is heightened in light of the following considerations: The volume of evidence available to guide clinical decisions continues to grow at a rapid pace ( figure 2)Sign in with Microsoft. Sign in with Open Athens. Sign in Another Way. If your organization permits Single Sign-On (SSO) for UpToDate, you may use your email address here. If not, please enter your Username.Acute pancreatitis should be suspected in patients with severe acute upper abdominal pain but requires biochemical or radiologic evidence to establish the diagnosis. This topic will review the clinical manifestations and diagnosis of acute pancreatitis. The etiology, pathogenesis, assessment of severity, and management of acute pancreatitis … UpToDate is an online clinical resource tool for physicians and patients that provides information on various specialties and topics. Click on one of the specialties to see sections associated with each, such as Practice Changing UpDates, What's New, Patient Education, Calculators, and Drug Information. Mar 25, 2024 · Acute treatment of migraine in adults without hemiplegic or brainstem aura. Algorithm 1. The abortive (symptomatic) therapy of migraine ranges from the use of simple analgesics such as nonsteroidal anti-inflammatory drugs (NSAIDs) or acetaminophen to triptans, antiemetics, calcitonin gene-related peptide (CGRP) antagonists, lasmiditan, and ... INTRODUCTION — Herpes simplex virus type 1 (HSV-1) is a cause of recurrent vesiculoulcerative lesions of the oral or genital mucosa. It can also cause infection in the eye, skin, central nervous system, and/or visceral organs. This topic will review treatment and prevention of primary and recurrent HSV-1 infections in …UpToDate, the evidence-based clinical decision support resource from Wolters Kluwer, is trusted at the point of care by clinicians worldwide.INTRODUCTION. Vitamin D is a fat-soluble vitamin. Very few foods naturally contain vitamin D (fatty fish are the exception), so dermal synthesis is the major natural source of the vitamin. Vitamin D from the diet or dermal synthesis is biologically inactive and requires enzymatic conversion to active metabolites ( figure 1 ). UpToDate is an online clinical resource tool for physicians and patients that provides information on various specialties and topics. Click on one of the specialties to see sections associated with each, such as Practice Changing UpDates, What's New, Patient Education, Calculators, and Drug Information. The diagnosis of iron deficiency (low iron stores, as measured by iron studies or other testing) is a major public health goal and an important aspect of the care of many adults. This topic will review the causes of iron deficiency in adults and an approach to the diagnostic evaluation. Treatment of iron deficiency in adults is discussed ...The use of any anticoagulant is associated with an increased risk of bleeding, and bleeding complications can be life-threatening. Management of bleeding in individuals who are receiving a direct oral anticoagulant (DOAC) can be challenging because routine coagulation tests cannot generally be used to determine the degree of …CAUSES OF VITAMIN D DEFICIENCY. The main reasons for low levels of vitamin D are: Lack of vitamin D in the diet, often in conjunction with inadequate sun exposure. Reduced absorption of vitamin D from the intestines. Reduced processing of vitamin D due to kidney or liver disease.UpToDate is an online platform that offers evidence-based clinical information and decision support for health care professionals and patients. To use UpToDate, you need to …The judgment could add to the debate over marital rapeIntrauterine tamponade (with a balloon, packing, or vacuum) may be u Allergic conjunctivitis is caused by airborne allergens contacting the eye, which leads to immunoglobulin E (IgE) mediated local mast cell degranulation and allergic inflammation. It typically presents as bilateral ocular itching, redness, and watery discharge. This topic discusses the management of allergic conjunctivitis. Sep 7, 2022 · Chronic diarrhea is defined as three or The judgment could add to the debate over marital rape in India. India’s supreme court has marked a big step forward in the fight against the sexual exploitation of minors. In a la... Potassium enters the body via oral intake or intravenous infusion,

Mar 15, 2023 · Vaginal yeast infections (also called yeast vaginitis or vaginal candidiasis) are a common problem in women. The most common symptoms are itching and irritation of the vulva and around the opening of the vagina. Vaginal yeast infections usually occur as infrequent episodes, but can recur frequently and may cause chronic persistent symptoms. It may also be associated with acute stress, medication or substances, poor sleep habits, or changes in the sleep environment. The diagnosis of insomnia requires three main components: persistent sleep difficulty, adequate sleep opportunity, and associated daytime dysfunction. The clinical features, diagnosis, and differential diagnosis of ...Google today introduced a new mobile management and security solution, Android Enterprise Essentials, which, despite its name, is actually aimed at small to medium-sized businesses...UpToDate, the evidence-based clinical decision support resource from Wolters Kluwer, is trusted at the point of care by clinicians worldwide.

Patient Education. UpToDate offers two levels of content for patients: The Basics are short overviews. They are written in accordance with plain language principles and answer the four or five most important questions a person might have about a medical problem. Beyond the Basics are longer, more detailed reviews.Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options.UpToDate, electronic clinical resource tool for physicians and patients that provides information on Adult Primary Care and Internal Medicine, Allergy and Immunology, Cardiovascular Medicine, Emergency Medicine, Endocrinology and Diabetes, Family Medicine, Gastroenterology and Hepatology, Hematology, Infectious Diseases, ……

Reader Q&A - also see RECOMMENDED ARTICLES & FAQs. UpToDate is an online clinical resource t. Possible cause: Hydroxocobalamin (vitamin B12a supplement and cyanide antidote): Pediat.

Acute pancreatitis should be suspected in patients with severe acute upper abdominal pain but requires biochemical or radiologic evidence to establish the diagnosis. This topic will review the clinical manifestations and diagnosis of acute pancreatitis. The etiology, pathogenesis, assessment of severity, and management of acute pancreatitis are ...Indices Commodities Currencies StocksINTRODUCTION. —. Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality worldwide. The clinical presentation of CAP varies, ranging from mild pneumonia characterized by fever and productive cough to severe pneumonia characterized by respiratory distress and sepsis.

Treatment of osteomyelitis includes consideration of issues related to debridement, management of infected foreign bodies (if present), antibiotic selection, and duration of therapy; these issues are discussed in the following sections. General issues related to treatment of osteomyelitis are discussed here.UpToDate, electronic clinical resource tool for physicians and patients that provides information on Adult Primary Care and Internal Medicine, Allergy and Immunology, Cardiovascular Medicine, Emergency Medicine, Endocrinology and Diabetes, Family Medicine, Gastroenterology and Hepatology, Hematology, Infectious Diseases, …

For over 30 years, clinicians around the world have trusted the evid Osteoporosis is caused by the cumulative effect of bone resorption in excess of bone formation. Bisphosphonates inhibit bone resorption with relatively few side effects. As a result, they are widely used to prevent osteoporotic fractures. The use of bisphosphonates for the management of osteoporosis will be reviewed here.Jun 10, 2022 · INTRODUCTION. —. Tetanus is a nervous system disorder characterized by muscle spasms that is caused by the toxin-producing anaerobe Clostridium tetani, which is found in the soil. The clinical features of tetanus and its relationship to traumatic injuries were well known among the ancient Greeks and Egyptians and to many clinicians before the ... Pneumococcal vaccination is indicated for adults with risk factors fMar 28, 2024 ... Outline · Suboptimal response · - Adju Normally during sleep, air moves in and out through the nose, throat, and lungs at a regular rhythm. In a person with sleep apnea, air movement is periodically reduced or stopped. There are two types of sleep apnea, obstructive sleep apnea and central (non-obstructive) sleep apnea; some forms of apnea involve both types (a “mixed” apnea). UpToDate contains a number of patient education articles that discu UpToDate, electronic clinical resource tool for physicians and patients that provides information on Adult Primary Care and Internal Medicine, Allergy and Immunology, Cardiovascular Medicine, Emergency Medicine, Endocrinology and Diabetes, Family Medicine, Gastroenterology and Hepatology, Hematology, Infectious Diseases, … UpToDate is a trusted source of clinical information for UpToDate® registrants and Individual subscribers canAbout UpToDate UpToDate is the evidence-based, point-of-care resource This generally includes an acute change in one or more of the following cardinal symptoms: Cough increases in frequency and severity. Sputum production increases in volume and/or changes character. Dyspnea increases. The management of patients with exacerbations of COPD is discussed here. A table to assist with emergency …UpToDate is a trusted source of clinical information for health professionals. However, the page you are looking for can't be found. Try searching for a different topic or language. Dec 11, 2023 · Patient level information — UpToDate offers two t UpToDate, electronic clinical resource tool for physicians and patients that provides information on Adult Primary Care and Internal Medicine, Allergy and Immunology, Cardiovascular Medicine, Emergency Medicine, Endocrinology and Diabetes, Family Medicine, Gastroenterology and Hepatology, Hematology, Infectious Diseases, Nephrology and Hypertension, Neurology, Obstetrics, Gynecology, and Women ... Second dose of a 2023-2024 COVID-19 vaccine for individuals 65 years Patient Education. UpToDate offers two levels of content for Smoking cessation is associated with clear health benefits. Cigarette smoking is the leading preventable cause of death in the United States and worldwide. Tobacco use increases the risk of many acute and chronic diseases, including cancers at many sites. Medications, including nicotine replacement, varenicline, and bupropion, …This topic will review the clinical presentation, diagnosis, and initial evaluation of diabetes in nonpregnant adults. Screening for and prevention of diabetes, the etiologic classification of diabetes mellitus, the treatment of diabetes, as well as diabetes during pregnancy are discussed separately. (See "Screening for type 2 diabetes mellitus" .)